TY  - GEN
AU  - Gollery, Martin
TI  - Handbook of hidden Markov models in bioinformatics
SN  - 9781584886846
U1  - 570.285 
PY  - 2013///
CY  - London
PB  - CRC Press
KW  - Bioinformatics
KW  - Computational biology
KW  - Markov processes
N1  - The book begins with discussions on key HMM and related profile methods, including the HMMER package, the sequence analysis method (SAM), and the PSI-BLAST algorithm. It then provides detailed information about various types of publicly available HMM databases, such as Pfam, PANTHER, COG, and metaSHARK. After outlining ways to develop and use an automated bioinformatics workflow, the author describes how to make custom HMM databases using HMMER, SAM, and PSI-BLAST. He also helps you select the right program to speed up searches. The final chapter explores several applications of HMM methods, including predictions of subcellular localization, posttranslational modification, and binding site.
By learning how to effectively use the databases and methods presented in this handbook, you will be able to efficiently identify features of biological interest in your data

N2  - Table of Contents
Introduction to HMMs and Related Profile Methods 
Profile HMMs 
HMM Methods 
HMM Databases 
Building an Analytical Pipeline 
Building Custom Databases 
Speeding Your Searches 
Other Uses of HMMs in Bioinformatics
(https://www.crcpress.com/Handbook-of-Hidden-Markov-Models-in-Bioinformatics/Gollery/9781584886846)
ER  -